Upper urinary tract tumour: Outcomes after radical surgery & peri-operative chemotherapy
Poster Session 88
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Location:Room Munich, North Hall (Level 1)
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Chairs:
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Aims and objectives of this session To date, radical surgery represents the only potentially curable therapeutic intervention for patients with urothelial carcinoma of the upper tract (UTUC). Although the role of lymphadenectomy in these tumors has not yet been clarified, recent evidence has shown that in patients with locally advanced tumors, it improves staging and consequently could help in selecting patients for adjuvant chemotherapy. UTUC and bladder carcinomas, are considered to be relatively chemosensitive. In fact, most of the data regarding the clinical efficacy of chemotherapy in the neoadjuvant and adjuvant settings are based on outcomes from the treatment of bladder UC. Contrary to what has been demonstrated for bladder cancer, there have been no convincing reported effects of neoadjuvant chemotherapy for UTUCs. Adjuvant chemotherapy achieves a remission rate of up to 50% but has minimal impact on survival.
Systemic recurrences are common in this disease, however, and it is therefore reasonable to consider perioperative chemotherapy in an effort to decrease a patient’s risk of recurrence. The aim of this session is to discuss modern outcomes after radical nephroureterectomy and perioperative chemotherapy. - Poster viewing of 20 minutes. Presentations will take place on stage. Standard presentations are 2 minutes in length, followed by 2 minutes for discussion. Extended presentations (*) are 3 minutes in length, followed by 3 minutes for discussion.
Institutes: 1Brigham and Women Hospital, Dept. of Urology, Boston, United States of America, 2Dana Farber Cancer Institute, Dept. of Genito Urinary Medical Oncology, Boston, United States of America, 3Hôpitaux Universitaires La Pitié-Salpêtrière, Dept. of Urology, Paris, France
Institutes: 1Baylor College of Medicine, Scott Dept. of Urology, Houston, United States of America, 2Baylor College of Medicine, Human Genome Sequencing Center, Houston, United States of America, 3MD Anderson Cancer Center, Dept. of Bioinformatics and Computational Biology, Houston, United States of America, 4Baylor College of Medicine, Dept. of Pathology, Houston, United States of America, 5MD Anderson Cancer Center, Institute for Personalized Cancer Therapy, Houston, United States of America, 6MD Anderson Cancer Center, Dept. of Pathology, Houston, United States of America, 7MD Anderson Cancer Center, Dept. of Urology, Houston, United States of America
Institutes: 1Peking University First Hospital, Dept. of Urology, Beijing, China, 2Peking University First Hospital, Dept. of Geriatrics, Beijing, China, 3Peking University First Hospital, Dept. of Pathology, Beijing, China
Institutes: 1Medical University of Vienna, Dept. of Urology, Vienna, Austria, 2Pitié-Salpétrière, Assistance-Publique Hôpitaux De Paris, Dept. of Urology, Paris, France, 3Hôpital Privé De La Louvière, Générale De Santé, Dept. of Urology, Lille, France, 4Hopital Mondor, Dept. of Urology, Creteil, France, 5CHU Rennes, Dept. of Urology, Rennes, France, 6Technische Universität Dresden, Dept. of Urology, Dresden, Germany, 7Jagiellonian University, Dept. of Urology, Krakow, Germany, 8Urological Research Institute, Vita-Salute University, San Raffaele Scientific, Dept. of Urology, Milan, Italy, 9Urological Research Institute, Vita-Salute University, San Raffaele Scientifi, Dept. of Urology, Milan, Italy, 10“Regina Elena” National Cancer Institute, Dept. of Urology, Rome, Italy, 11Kitasato University School of Medicine, Dept. of Urology, Kanagawa, Japan, 12University of Montreal, Dept. of Urology, Montreal, Canada
Institutes: 1Cliniques Universitaires Saint-Luc, Dept. of Urology, Brussels, Belgium, 2Vita Salute San Raffaele, Dept. of Urology, Milan, Italy, 3Medical University Vienna, Dept. of Urology, Vienna, Austria, 4Hôpital Pitié-Salpétrière, Dept. of Urology, Paris, France, 5University of Warwick, Cancer Research Center, Coventry, United Kingdom, 6Dana-Farber Cancer Institute, Dept. of Medical Oncology, Havard, United States of America, 7San Camillo and Forlanini Hospitals, Dept.of Medical Oncology, Rome, Italy, 8EORTC, Dept. of Statistics, Brussels, Belgium
Institutes: 1Medical University of Vienna, Dept. of Urology, Vienna, Austria, 2Pitié-Salpétrière, Assistance-Publique Hôpitaux, Dept. of Urology, Paris, France, 3Hôpital Privé De La Louvière, Dept. of Urology, Lille, France, 4Hopital Mondor, Dept. of Urology, Creteil, France, 5CHU Rennes, Dept. of Urology, Rennes, France, 6Technische Universität Dresden, Dept. of Urology, Dresden, Germany, 7Jagiellonian University, Dept. of Urology, Krakow, Poland, 8Vita-Salute University, San Raffaele Scientifi, Dept. of Urology, Milan, Italy, 9Regina Elena National Cancer Institute, Dept. of Urology, Rome, Italy, 10Kitasato University School of Medicine, Dept. of Urology, Kanagawa, Japan, 11University of Montrea, Dept. of Urology, Montreal, Canada
Institutes: 1Tohoku University Graduate School Of Medicine, Dept. of Urology, Sendai, Japan, 2Japan Community Health Care Organization Sendai Hospital, Dept. of Urology, Sendai, Japan, 3Sendai City Hospital, Dept. of Urology, Sendai, Japan, 4Osaki Citizen Hospital, Dept. of Urology, Osaki, Japan, 5Yamagata Prefectural Central Hospital, Dept. of Urology, Yamagata, Japan, 6Kesennuma City Hospital, Dept. of Urology, Kesennuma, Japan, 7Miyagi Cancer Center, Dept. of Urology, Natori, Japan, 8Hachinohe City Hospital, Dept. of Urology, Hachinohe, Japan, 9Tohoku Rosai Hospital, Dept. of Urology, Sendai, Japan, 10Sendai Medical Center, Dept. of Urology, Sendai, Japan, 11Senenrifu Hospital, Dept. of Urology, Rifu, Japan, 12Ogachi Central Hospital, Dept. of Urology, Yuzawa, Japan, 13Japanese Red Cross Sendai Hospital, Dept. of Urology, Sendai, Japan, 14Shirakawa Kosei General Hospital, Dept. of Urology, Shirakawa, Japan, 15Iwate Prefectural Iwai Hospital, Dept. of Urology, Ichinoseki, Japan
Institutes: 1CHU Rennes, Dept. of Urology, Rennes, France, 2CH Orleans, Dept. of Urology, Orleans, France, 3CHU Tours, Dept. of Urology, Tours, France, 4PItié Salpétrière Hospital, Dept. of Urology, Paris, France, 5CHU Lille, Dept. of Urology, Lille, France, 6Pitié Salpétrière Hospital, Dept. of Urology, Paris, France