Session

Upper urinary tract tumor: Let's manage it endoscopically!

Poster Session 78

  • Location:
    Room Munich, North Hall (Level 1)
  • Chairs:
     A. Breda, Barcelona (ES)
     M. Rink, Hamburg (DE)
     O. Traxer, Paris (FR)
  • Aims and objectives of this session

    The rise in clinical awareness about upper tract urothelial carcinomas (UTUCs) is in part due to the significant technological improvement in endoscopes used to examine the upper urinary tract. The development of small calibre, fibre-optic flexible digital ureteroscopes has expanded the management options for UTUC. Advances in distal-tip deflection and scope durability, combined with improved laser technology, have enhanced the role of flexible ureteroscopy from a diagnostic to a therapeutic procedure. No longer can radical nephoureterectomy (RNU) be considered the ‘gold standard’ treatment for all UTUCs.
    The challenge is to identify pre-operatively which patients and tumours would be more appropriately managed in a conservative manner via endoscopic techniques and laser ablation or segmental ureterectomy in certain cases. Based on the available evidence UTUC patients with contralateral normal kidney can be classified at time of diagnosis as having “low-risk UTUC” or “high-risk UTUC”. Patients with low-risk disease should be offered (as default) endoscopic management with laser ablation and topical MMC or BCG as an option. The aim of this session is to review available data to better select UTUC suitable for kidney-sparing treatment.

  • Poster viewing of 20 minutes. Presentations will take place on stage. Standard presentations are 2 minutes in length, followed by 2 minutes for discussion. Extended presentations (*) are 3 minutes in length, followed by 3 minutes for discussion.
1031
Assessment of clinical screening criteria and point of care testing for Lynch syndrome-associated upper tract urothelial cancer

By: Metcalfe M.1, Rao P.2, Mork M.3, Xiao L.4, Broaddus R.2, Matin S.1

Institutes: 1University of Texas Md Anderson Cancer Center, Dept. of Urology, Houston, United States of America, 2University of Texas Md Anderson Cancer Center, Dept. of Pathology, Houston, United States of America, 3University of Texas Md Anderson Cancer Center, Dept. of Genetics, Houston, United States of America, 4University of Texas Md Anderson Cancer Center, Dept. of Statistics, Houston, United States of America

1032
Ureteroscopic biopsy of upper tract urothelial carcinoma is associated with increased intravesical recurrences on follow-up: A multi institutional Suture group study

By: Anbarasan T.1, Shaikh N.2, Mcluckie S.1, Shams-Uddin A.3, Alcorn J.4, Jain S.5, Biyani C.S.4, Nabi G.1

Institutes: 1University of Dundee, School of Medicine, Academic Section of Urology, Division of Cancer Research, Dundee, United Kingdom, 2United Lincolnshire NHS Trust, Pilgrim Hospital, Dept. of Urology, Lincolnshire, United Kingdom, 3Imperial College Healthcare NHS Trust, Charing Cross Hospital, Dept. of Urology, London, United Kingdom, 4Mid Yorkshire Hospitals NHS Trust, Dept. of Urology, Wakefield, United Kingdom, 5Leeds Teaching Hospitals NHS Trust, Dept. of Urology, Leeds, United Kingdom

1033
Confocal laser endomicroscopy in upper tract urothelial cancer (UTUC)

By: Breda A.1, Territo A.1, Manfredi M.1, Guttilla A.1, Quaresima L.1, Gaya J.1, Algaba F.2, Palou J.1, Villavicencio H.1

Institutes: 1Fundaciò Puigvert, Dept. of Urology, Barcelona, Spain, 2Fundaciò Puigvert, Divison of Pathology, Barcelona, Spain

1034
Is ureteroscopy essential prior to nephroureterectomy for upper tract transitional cell carcinoma?

By: Veeratterapillay R., Thompson E., Shakoor R., Gandiya T., Rogers A., Thomas D.

Institutes: Freeman Hospital, Dept. of Urology, Newcastle upon Tyne, United Kingdom

* 1035
Diagnostic ureteroscopy for upper tract urothelial carcinoma is independently associated with intravesical recurrence after radical nephroureterectomy

By: Li X-S., Zhou L., Su X., Liu P., Fang D.

Institutes: Peking University First Hospital, Dept. of Urology, Beijing, China

1036
Fluorescence in situ hybridization for upper urinary tract urothelial carcinoma - an important diagnostic tool in clinical practice

By: Bonaventura A, Jung V., Ohlmann C.-H., Stöckle M., Junker K.

Institutes: Saarland University Medical Center, Dept. of Urology, Homburg, Germany

* 1037
Thulium laser treatment of upper urinary tract transitional cell carcinoma

By: Maruccia S.2, Saredi G.3, Parma P.4, Casellato S.2, Bozzini G.1

Institutes: 1Humanitas Mater Domini, Dept. of Urology, Castellanza, Italy, 2Istituti Clinici Zucchi, Dept. of Urology, Monza, Italy, 3Ospedale Varese, Dept. of Urology, Varese, Italy, 4Ospedale Mantova, Dept. of Urology, Mantova, Italy

1038
CT urography understages, and URS with biopsy undergrades upper tract urothelial carcinoma in the preoperative evaluation before nephroureterectomy

By: Almas B.1, Loe A.1, Reisæter L.2, Halvorsen O.J.3, Beisland C.1

Institutes: 1Haukeland University Hospital, Dept. of Urology, Bergen, Norway, 2Haukeland University Hospital, Dept. of Radiology, Bergen, Norway, 3Haukeland University Hospital, Dept. of Pathology, Bergen, Norway

1039
Positive predictive value of CT urography for upper tract urothelial carcinoma diagnosis using diagnostic ureteroscopy as the reference standard

By: Mintz I.1, Reshetnyak O.1, Kabha M.1, Chang C.T.2, Sophie B.3, Diego M.3, Mabjeesh N.1, Matzkin H.1, Liao J.2, Sofer M.1

Institutes: 1Tel Aviv Sourasky Medical Center, Tel-Aviv University, Dept. of Urology, Tel-Aviv, Israel, 2Stanford Health Care, Stanford University, Dept. of Urology, Stanford, United States of America, 3Tel Aviv Sourasky Medical Center, Tel-Aviv University, Dept. of Radiology, Tel-Aviv, Israel

* 1040
Results of second line topical therapy for upper tract urothelial carcinoma (UTUC)

By: Balasubramanian A., Metcalfe M., Wagenheim G., Xiao L., Papadopoulos J., Navai N., Davis J., Karam J., Kamat A., Wood C., Dinney C., Matin S.

Institutes: University of Texas Md Anderson Cancer Center, Dept. of Urology, Houston, United States of America

1042
A systematic review of the impact of pre-operative diagnostic ureteroscopy on bladder recurrence after nephroureterectomy for upper tract transitional cell carcinoma

By: Birks T., Jenkins J., Davenport K.

Institutes: Cheltenham General Hospital, Dept. of Urology, Cheltenham, United Kingdom

1043
Statin use and prognosis of the upper tract urothelial carcinoma in a Finnish population-based cohort

By: Hurskainen H.2, Kotsar A.3, Tammela T.1, Murtola T.1

Institutes: 1Tampere University Hospital, Dept. of Urology, Tampere, Finland, 2University of Tampere, School of Medicine, Tampere, Finland, 3Tarto University Hospital, Dept. of Urology, Tarto, Estonia