Session

Receptors and targets in functional urology

Poster Session 15

  • Location:
    Room Berlin, North Hall (Level 1)
  • Chairs:
     C. Cruz, Porto (PT)
     D. Daly, Lancashire (GB)
     K. Monastyrskaya, Bern (CH)
  • Aims and objectives of this session

    The search for new pharmacological targets continues. Receptors and new mechanisms are being discussed in this session.

  • Poster viewing of 20 minutes. Presentations will take place on stage. Standard presentations are 2 minutes in length, followed by 2 minutes for discussion. Extended presentations (*) are 3 minutes in length, followed by 3 minutes for discussion.
193
Estradiol releasing hydrogel as a proangiogenic substitute for fat flaps used in urogenital reconstruction

By: Eke G.2, Mangir N.1, Hasirci N.3, Chapple C.4, Hasirci V.5, Macneil S.1

Institutes: 1Kroto Research Institute, Dept. of Materials Science and Engineering, Sheffield, United Kingdom, 2Middle East Technical University (METU), Dept. of Biotechnology & BIOMATEN, METU Center of Excellence In Biomaterials and Tissue Engineering, Ankara, Turkey, 3METU, Dept. of of Biotechnology, Chemistry & BIOMATEN, METU Center of Excellence In Biomaterials and Tissue Engineering, Ankara, Turkey, 4Royal Hallamshire Hospital, Dept. of Urology, Sheffield, United Kingdom, 5METU, Dept. of of Biotechnology, Biological Sciences & BIOMATEN, METU Center of Excellence In Biomaterials and Tissue Engineering, Ankara, Turkey

194
9-Phenanthrol modifies rat bladder function independent of TRPM4

By: Deruyver Y.1, Uvin P.1, Pinto S2, Van Ranst N.2, Franken J.1, Gevaert T.1, Everaerts W.1, Voets T.2, De Ridder D.1, Vennekens R.2

Institutes: 1KU Leuven, Laboratory of Experimental Urology, Leuven, Belgium, 2KU Leuven, Laboratory of Ion Channel Research, Leuven, Belgium

195
Supraspinal effects of dopamine uptake inhibitor on the micturition reflex in rats

By: Honda M.1, Yoshimura N.2, Kimura Y.1, Kawamoto B.1, Tsounapi P.1, Hikita K.1, Shimizu S.3, Shimizu T.3, Saito M.3, Chancellor M.4, Takenaka A.1

Institutes: 1Tottori University Faculty of Medicine, Dept. of Urology, Yonago, Japan, 2University of Pittsburgh, Dept. of Urology, Pittsburgh, United States of America, 3Kochi Medical School, Dept. of Pharmacology, Nankoku, Japan, 4William Beaumont Hospital, Dept. of Urology, Royal Oak, United States of America

196
Role of supraspinal and spinal group III metabotropic glutamate receptor in micturition reflex in urethane-anesthetized rats

By: Honda M.1, Kimura Y.1, Kawamoto B.1, Tsounapi P.1, Hikita K.1, Saito M.2, Takenaka A.1

Institutes: 1Tottori University Faculty of Medicine, Dept. of Urology, Yonago, Japan, 2Kochi Medical School, Dept. of Pharmacology, Nankoku, Japan

* 197
KPR-2579, a novel TRPM8 antagonist, inhibits hyperactivity of the primary bladder afferent nerves induced by acetic acid in rats

By: Aizawa N.1, Fujimori Y.2, Kobayashi J.2, Nakanishi O.2, Hirasawa H.2, Homma Y.3, Igawa Y.1

Institutes: 1The University of Tokyo Graduate School of Medicine, Dept. of Continence Medicine, Tokyo, Japan, 2Kissei Pharmaceutical Co., Ltd., Discovery Research R&D, Azumino, Japan, 3The University of Tokyo Graduate School of Medicine, Dept. of Urology, Tokyo, Japan

198
Does TRP channel play a role in cooling-induced contraction of human detrusor smooth muscle?

By: Kajioka S., Maki T., Lee K., Takahashi R., Ito M.

Institutes: Kyushu University, Dept. of Urology, Fukuoka, Japan

* 199
Novel three-mRNA and three-miRNA signatures accurately identify urodynamically-defined bladder phenotypes and correspond to functional improvement after deobstruction

By: Moltzahn F.1, Burkhard F.1, Hashemi Gheinani A.2, Koeck I.2, Monastyrskaya K.2

Institutes: 1University Hospital Bern, Dept. of Urology, Bern, Switzerland, 2Urology Research Laboratory, Dept. of Clinical Research, Bern, Switzerland

200
Withdrawn

By:

Institutes:

201
The water avoidance stress induces bladder pain due to a prolonged adrenergic (alpha1A) stimulation of the bladder

By: Matos R.1, Serrão P.2, Rodrigues L.3, Birder L.A.4, Cruz F.5, Charrua A.6

Institutes: 1Faculty of Medicine of University of Porto, Dept. of Biomedical Science, Porto, Portugal, 2University of Porto, Dept. of Pharmacology & Therapeutics and MedInUP, Porto, Portugal, 3University of Southern California, Dept. of Urology and Obstetrics and Gynecology, Los Angeles, United States of America, 4University of Pittsburgh School of Medicine, Dept. of Medicine and Pharmacology-Chemical Biology, Pittsburgh, United States of America, 5University of Porto and CHSJ, Dept. of Biomedical Science and I3S-IBMC, Porto, Portugal, 6University of Porto, Dept. of Biomedical Science and I3S-IBMC, Porto, Portugal

202
Validation of TNF-α as the top upstream regulator of bladder remodelling during outlet obstruction-induced lower urinary tract dysfunction

By: Koeck I.1, Hashemi Gheinani A.1, Burkhard F.2, Monastyrskaya K.2

Institutes: 1Urology Research Laboratory, Dept. of Clinical Research, Bern, Switzerland, 2University Hospital Bern, Dept. of Urology, Bern, Switzerland

203
Morphological and functional restoration comparison between a novel bilayer chitosan and bladder acellular matrix graft as scaffolds in a rat bladder augmentation model

By: Xiao D.1, Wang Q.2, Zhang M.1, Zhou Z.1, Lu M.1

Institutes: 1Renji Hospital, Dept. of Urology and Andrology, Shanghai, China, 2Shanghai 9th People’s Hospital, Dept. of Urology, Shanghai, China

204
Effects of litoxetine on acetic acid-induced detrusor overactivity and striated anal sphincter functions in rabbits: Comparison with duloxetine

By: Pérez-Martínez F.2, Lluel P.1, Palea S.3, Vela-Navarrete R.2

Institutes: 1Urosphere, Dept of Pharmacology, Toulouse, France, 2Universidad Autónoma De Madrid, Dept. of Urology, Madrid, Spain, 3Palea Pharma & Biotech Consulting, , Toulouse, France

205
The stem cell growth factor receptor KIT is not expressed on interstitial cells in bladder

By: Gevaert T.1, Vanstreels E.2, Daelemans D.2, Everaerts W.1, Van Der Aa F.1, Pintelon I.3, Timmermans J-P.3, Roskams T.4, Steiner C.5, Neuhaus J.5, De Ridder D.1

Institutes: 1UZ Leuven, Dept. of Urology, Leuven, Belgium, 2KU Leuven, Rega Institute For Medical Research, Leuven, Belgium, 3University of Antwerp, Dept. of Veterinary Sciences, Antwerp, Belgium, 4KU Leuven, Dept. of Pathology, Leuven, Belgium, 5University of Leipzig, Klinik Und Poliklinik Für Urologie, Leipzig, Germany